Rational
Design of Viral Inhibitors: Application to SARS
Targeting
the PDZ-ligand Domain of Avian Influenza A Viruses for Novel
Therapeutics
Ability
of Antibody Against Coxiella burnetii LPS to confer Protective
Immunity
Toward
Ideal Vaccines for Emerging and Biothreat Agents
Rickettsial
Infection of Humanized Mice
Development
of Recombinant Pandemic Influenza Vaccines
A
nonhuman primate model of Rickettsia prowazekii infection (epidemic
typhus)
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The
WIRED Grant program provides funding for promising research that
translates into the development of new vaccines, therapeutics,
and/or diagnostics directed against NIAID Category A, B, and
C agents. The funds will be used to conduct pilot studies, feasibility
studies, proof-of-concept, and preliminary research for innovative,
cutting-edge research in anticipation of supporting the WRCE
competing continuation application that will submitted in the
summer of 2008. These are highly-focused projects that are subject
to yearly review, and will not be funded beyond Feb. 28, 2009.
Like R21-type awards, WIRED grants are intended to encourage new,
exploratory and developmental research projects by providing support
for the early stages of their development. The main purpose of
the WIRED project awards is to promote new research in anticipation
of the WRCE competing continuation application. The Regional
Center for Excellence for Biodefense and Emerging Infectious Diseases
Research (RCE) program was initiated and funded by NIH/NIAID in
September of 2003, and the WRCE is one of ten RCEs.
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